New Approach to Aging: Scientists Restore Youthful Function to Old Cells
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Summary
Old cells of progeria patients are made young again, thanks to telomere lengthening technique.
Scientists recently rejuvenated old cells “young” using a new technique to make the cells regrow their telomeres, the protective ends of our chromosomes that naturally shorten with age.
The study marks a major step forward in controlling and reversing, the cellular aging process.
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Scientists at the Houston Methodist Research Institute have made a breakthrough in halting aging in human cells. Their research, published in the Journal of the American College of Cardiology, focused on telomeres, the protective structures at the ends of chromosomes that shorten with age. The team, led by Dr. John Cooke, studied cells from children with progeria, a genetic disease causing rapid aging.
Dr. Cooke explained that telomeres act as a cellular "time keeper," shortening with cell division and stress, eventually leading to cellular dysfunction. Children with progeria experience accelerated aging, exhibiting characteristics of an 80-year-old by their teenage years, including weakened bones, muscles, aged skin, and increased risk of cardiovascular problems.
The researchers used ribonucleic acid to stimulate the production of a protein that lengthens telomeres. This effectively stopped aging in the cells they studied. Dr. Cooke noted that the cells they worked with, obtained from a progeria research foundation, had the DNA of a 70-year-old. By extending the telomeres with the ribonucleic acid treatment, they rejuvenated the cells, improving their ability to divide, multiply, and function. Dr. Cooke believes this method holds promise for addressing other age-related issues as well.
Original Article: https://sputnikglobe.com/20170803/age-reversal-study-1056146105.html